Deblistering Solutions

Blister packs can be rejected for various reasons, such as empty pockets, wrong products, batch coding errors, failed leak tests, or inventory changes. When valuable tablets or capsules need to be recovered, it’s crucial to use gentle pressure during deblistering to avoid damaging the product or contaminating it with foil fragments.

Sepha offers a complete range of automatic, semi-automatic, and manual deblistering machines designed for fast, safe, and efficient recovery of products from all types of rejected blister packs—including push-through, child-resistant, and peelable varieties.

Explore the Sepha PressOut range to find the ideal solution for your needs and reduce costs in handling rejected blister packs.

The Sepha PressOut Manual Wide is a portable, tool-free manual machine designed to recover tablets and capsules from push-through blister packs efficiently.

Ideal for small batches, this machine feeds blister packs through rollers by turning a simple handle. As the packs pass through, the tablets or capsules are gently separated from the packaging waste.

Compatible with both thermoform/alu and coldform/alu blister packs, the PressOut Manual Wide is fully cGMP compliant and offers easy adjustment to suit different blister pack types.

Key Features

  • Portable and easy to adjust for any push-through blister pack
  • Fully cGMP compliant and simple to clean
  • Works with both thermoform/alu and coldform/alu blisters
  • User-friendly—no special skills required
  • Recovers products cleanly and hygienically
  • Perfect for small batch processing
  • Cost-effective solution

Technical Specifications

  • Blister Type: Push-through
  • Blister Layout: In-line or offset/diagonal (depending on pack)
  • Maximum Pack Size: Up to 170mm wide, unlimited length
  • Operating Speed: Up to 20 blister packs per minute
  • Operation: Manual, no power required
  • Construction: Stainless steel 316 and food-grade ABS in all product contact areas
  • Tooling Changeover: Quick 3-minute adjustment
  • Dimensions: 295mm (L) x 380mm (W) x 230mm (H)
  • Weight: 8kg (machine), 11.5kg (shipping)
  • Warranty: Includes 12-month warranty, with extended support available

Applications

Pharmacy Dispensing
Designed for efficient deblistering of bulk blister packs to refill monitored dosage systems (MDS) for individual patients in hospitals, nursing homes, and other care facilities. Also ideal for refilling cartridges in automated dispensing systems.

Clinical Trials
Enables safe recovery of valuable clinical trial drugs from unused blister packs. Supports repackaging of competing products for double-blind clinical studies.

Quality Control Testing
Used for testing packaging materials to ensure quality and reliability.

Pharmaceutical Production & Packaging
Perfect for recovering products from rejected blister packs due to empty pockets, seal failures, or batch coding errors. Helps reduce waste and improve yield by allowing repackaging of good products. Also supports managing surplus stock by converting blister contents into formats suited for different markets.

Waste Disposal
Facilitates safe separation of products from packaging at end-of-life, reducing disposal costs—especially important for toxic or hazardous products.

Benefits

Flexible Solutions
The Sepha PressOut Manual Wide offers great flexibility, easily adjustable to handle many different push-through blister pack formats. Its patented design means there’s no need to buy new change parts for each blister type, saving time and cost.

Pharmaceutical Production & Packaging
Ideal for recovering good product from rejected blister packs due to empty pockets, seal failures, or batch coding errors. This helps reduce waste and boosts overall product yield by enabling repackaging.

Pharmaceutical Distribution & Inventory Management
Different countries often receive the same drugs in blister packs with localized packaging. The PressOut Manual Wide helps manage changing market demands by safely deblistering surplus stock for repackaging in formats suited to other markets.

Waste Disposal
At the end of a product’s shelf life, safe disposal is crucial. Separating product from packaging—especially for toxic items—helps reduce costly disposal processes and supports responsible waste management.

The Sepha PressOut Semi-Automatic is a compact, portable, and tool-less deblistering machine designed for recovering tablets and capsules from push-through blister packs.

Ideal for small batch operations, this semi-automatic machine feeds blister packs through motor-driven rollers that gently push the tablets or capsules out while separating them from the packaging. It offers a quick and efficient deblistering rate of up to 30 packs per minute.

The system features a single, adjustable tooling setup that can be easily changed within 1–2 minutes, making it a practical solution for teams that require fast turnaround and simple operation.

Key Features

  • Portable & adaptable – Easily adjusts to suit any push-through blister pack format
  • Hygienic & cGMP compliant – Designed for easy cleaning and regulatory compliance
  • Versatile – Handles both thermoform/alu and coldform/alu blister types
  • User-friendly – No technical expertise required
  • Clean product recovery – Extracts tablets or capsules safely and hygienically
  • Perfect for small batches – Ideal for low-volume or trial runs
  • Cost-effective – An affordable solution for manual deblistering needs

Technical Specifications

  • Compatible Blister Type: Push-through
  • Blister Layouts: Supports in-line and offset/diagonal formats (depending on pack design)
  • Pack Size Range:
    • Minimum width: 30mm
    • Maximum width: 170mm
    • Unlimited length
    • Maximum height: 10mm
  • Speed: Processes up to 30 blister packs per minute
  • Operation: Semi-automatic
  • Construction: All product-contact parts made from 316 stainless steel and food-grade ABS
  • Tooling Changeover: Quick 3-minute setup
  • Power Supply: 110/230V single-phase
  • Dimensions: 320mm (L) × 320mm (W) × 240mm (H)
  • Weight:
    • Machine: 18kg
    • Shipping: 20kg
  • Warranty: 12 months (Extended warranty options available)

Benefits

Versatile & Cost-Effective
The Sepha PressOut Semi-Automatic is ideal for operations handling a variety of push-through blister formats. Its patented design adjusts easily—no need for extra tooling with every new pack type.

Gentle on Products
Designed to protect tablets and capsules, the system uses a smooth roller and guide mechanism to gently remove product with minimal pressure. Softer rollers are available for more delicate products.

Clean Separation
The machine keeps foil attached to the empty blister, ensuring clean separation. Recovered products and waste are collected separately, reducing contamination risks.

Health & Safety Friendly
Manual deblistering can lead to hand strain and repetitive injuries. The PressOut Semi-Automatic eliminates these risks, making the process safer and more comfortable for operators.

Portable & Easy to Use
Compact and lightweight, it can be easily moved between workstations. No air supply needed—just plug and go.

Hygienic Operation
Made from stainless steel and built to cGMP standards, the system is easy to clean and doesn’t require direct product handling.

The Sepha PressOut Universal is a fast, automated deblistering solution designed to recover tablets and capsules from a wide range of blister packs—including child-resistant and peelable formats.

With advanced, gentle cutting technology, it handles even the most fragile, high-value products with care. Capable of processing up to 50 blister packs per minute, it’s a smart and cost-effective option for pharmaceutical manufacturers looking to reduce waste and protect product integrity.

Trusted by some of the world’s leading pharma companies, the PressOut Universal stands out for its reliability, flexibility, and exceptional recovery rates.

Key Features

  • Fully automated with adjustable speed and settings
  • Efficiently removes tablets from all blister formats, including child-resistant packs
  • High-speed performance — up to 50 blister packs per minute
  • Automatic feeding system for continuous operation
  • Handles a wide range of blister designs and layouts
  • Integrated 316 stainless steel product collection bin for hygienic recovery
  • Zero contamination — product and waste remain fully separated
  • Built to cGMP standards for easy validation
  • Intuitive software for simple, reliable control
  • Optional temperature and humidity monitoring
  • Easy-access design for quick cleaning and fast product changeovers

Technical Specifications

Operation
Fully automatic

Compatible Blister Types
Push-through, child-resistant, peelable, and multi-product formats

Blister Layouts
Suitable for all layouts

Pack Size Range

  • Minimum: 82mm (L) x 33mm (W)
  • Maximum: 140mm (L) x 105mm (W)

Speed
Processes up to 50 blister packs per minute

Construction
High-grade stainless steel (316 & 304) for hygiene and durability

Tooling Changeover
Quick changeover in approximately 5 minutes

User Interface
7” full-colour TFT touchscreen for easy operation

Utilities

  • Power: 110/230V Single Phase AC, 50/60 Hz
  • Air Supply: Minimum 450L/min at 0.6 Mpa (ISO8573-1:2010 Class 2)

Dimensions
660mm (L) x 960mm (W) x 1550mm (H)

Weight

  • Machine: 230kg
  • Shipping: 330kg

Warranty
Supplied with a 12-month warranty (extended warranties available)

Key Benefits

Handles All Blister Types
Easily processes child-resistant, peelable, curved, and heavy-duty alu/alu blister packs.

Fast & Automatic
Deblisters up to 50 packs per minute with automatic feeding—ideal for high-volume production.

Protects Fragile Products
A gentle press-out process that partially cuts the foil before extraction, reducing pressure on delicate or high-value tablets and capsules.

Keeps Product Clean & Separate
Foil stays attached to the blister during removal, ensuring clean separation. Waste and recovered products are collected independently for better hygiene.

Improves Workplace Safety & Morale
Eliminates the risk of finger strain or injury from manual deblistering. Frees up staff from repetitive, manual tasks.

Designed for Hygiene
Made from stainless steel and built to cGMP standards, the machine is easy to clean and maintain. No direct handling of product is required.

The Sepha PressOut Universal Mini is a bench-top automated deblistering machine, specially designed for recovering small batches of high-value tablets and capsules from a wide range of blister packs — including child-resistant, peelable, senior-friendly, paper-backed, and alu/alu formats.

Using the same precise cutting technology as the larger PressOut Universal, the Mini version is ideal for short production runs. It processes up to 16 blister packs per minute, with gentle, low-cost tooling that’s easy to switch. This helps protect fragile products from damage and avoids contamination.

Perfect for operations with frequent product changeovers, the PressOut Universal Mini offers an efficient, reliable solution to reduce waste and recover valuable product safely.

Key Features

  • Processes up to 16 blister packs per minute
  • Compact, bench-top design – ideal for limited space
  • Handles peelable and child-resistant blister packs
  • Automatic feeding for smooth operation
  • User-friendly Allen Bradley touchscreen interface
  • Quick and easy tooling setup and changeover
  • Easy to clean with full access to all components
  • Built to cGMP standards for quality compliance
  • Low-cost tooling for cost-effective use
  • Optional mobile workstation for added flexibility
  • Designed to prevent product contamination

Technical Specifications

  • Operation: Fully automatic
  • Compatible Blister Types: Push-through, child-resistant, peelable, and multi-product formats
  • Blister Layout: Suitable for all layouts
  • Pack Size Range:
    – Minimum: 82mm (L) x 33mm (W)
    – Maximum: 140mm (L) x 105mm (W)
  • Speed: Up to 16 blister packs per minute
  • Construction: High-quality stainless steel (Grade 316 & 304)
  • Tooling Changeover: Fast 5-minute setup
  • User Interface: Intuitive 4″ LCD touchscreen
  • Power Supply: 110/230V single-phase AC, 50/60 Hz
  • Air Supply: 6 Bar
  • Dimensions: 660mm (L) x 560mm (W) x 690mm (H)
  • Machine Weight: Approx. 80kg
  • Shipping Weight: 112.5kg
  • Warranty: 12-month warranty included (extended options available)

Key Benefits

  • Handles Child-Resistant and Complex Blisters
    Designed to work with a wide range of blister formats—including curved, peelable, and heavy-duty alu/alu packs.
  • Efficient & Automatic
    Deblisters up to 15 packs per minute with automated feeding for seamless operation.
  • Protects Fragile Products
    Uses a gentle cutting method that minimizes pressure on sensitive tablets and capsules, helping reduce product damage.
  • Clean Separation
    Foil remains attached to the blister during deblistering, while product and waste are collected separately to prevent contamination.
  • Improves Workplace Safety
    Reduces the risk of manual handling injuries such as finger strain and repetitive stress, enhancing operator safety and comfort.
  • Hygienic by Design
    Made from stainless steel and fully cGMP compliant, ensuring easy cleaning and minimal operator contact with recovered product.

The Sepha Clic-Open is a compact, easy-to-use ampoule opener designed to safely snap off the tops of glass ampoules—without leaving sharp edges. It’s a must-have tool for anyone handling liquid medications in ampoules, including:

  • Nurses
  • Doctors
  • Paramedics
  • Midwives
  • First aiders
  • Ambulance staff
  • Patients

Why Choose Clic-Open?

  • Prevents injuries – Protects fingers from glass cuts and sharp edges
  • Clean & hygienic – Reduces the risk of contamination
  • Durable – Each unit opens up to 200 ampoules
  • Versatile – Works with standard and “easy-open” ampoules
  • Effortless – No special skills required

Marketing & Promotional Use

The Sepha Clic-Open makes an excellent branded giveaway for pharmaceutical companies. Add your company or product logo for instant brand visibility every time a medic opens an ampoule. Ideal for:

  • Medical exhibitions & events
  • Sales team promotions
  • Inclusion in injectable patient kits

It’s a thoughtful, practical tool that promotes safety and builds customer loyalty.

How It Works

  1. Insert the ampoule neck into the jaws of the Clic-Open.
  2. Press the upper jaw to lightly score the neck with the internal tungsten carbide blade.
  3. Use the lower jaw as leverage to snap open the ampoule.
  4. Push the plunger to eject the ampoule top into a sharps container.

No squeezing required—just a clean break, every time.